The driver of a motorcycle is fighting for his life following a serious collision late Wednesday afternoon.

London police say a pick-up and cube van were sitting side-by-side at a stop light on Wonderland Road just south of Oxford Street.

Witnesses say the bike collided with the back of the pick-up and was propelled through the air into the side of the cube van.

Police say the driver sustained serious upper-body and head injuries.

Wonderland Road remains closed in both directions between Oxford Street and Riverside Drive while the police continue their investigation.

There were no other injuries reported.