St. Thomas police are calling it the largest drug operation in the force's history.
Over $466,000 worth of crystal meth, fentanyl and cocaine were seized.
Police say 19 people are facing nearly 100 drug-related charges.
Police are still looking to arrest two people, a 41-year old St.Thomas woman and a 40-year old woman.
CTV London will have a full report at 6 p.m.