Provincial Police have identified the deceased in Monday's 402 collision as 34-year-old Johnathan James Wright of London.
The crash happened just after 3 p.m. Monday, involving two tractor trailers and two vehicles.
One person is dead and five others had to be taken to the hospital for non life-threatening injuries.
The eastbound lanes were closed just east of Colonel Talbot Road until roughly 10 p.m. Monday.
The westbound lanes were not affected and the eastbound lanes reopened overnight.
More photos from the scene can be found in our gallery here.