The province's Special Investigations Unit (SIU) has invoked its mandate, following a domestic incident in Thamesford.
At 4:26 Friday monring, Oxford OPP were called to 5 Middleton Street in Thamesford for a domestic disturbance.
According to police, the man sustained self-inflicted life threatening injuries while dealing with officers.
Police did not sustain any injuries.
Officers immediately administered first aid and called an ambulance.
The man was transported to a London hospital.
The SIU invokes its mandate when police officers are involved in incidents where someone has been seriously hurt or dies.