Ontario researchers say they've found what causes long-COVID symptoms
Researchers at Western University in London, Ont., say they have identified for the first time the cause of long COVID symptoms.
According to a press release issued Tuesday by Western, the LIVECOVIDFREE study, which is based at five centres throughout Ontario and spearheaded by Western professor Grace Parraga, is the largest MRI study of patients afflicted with long COVID.
The use of MRI technology — combined with inhaled xenon gas — allowed researchers to see that long-COVID symptoms are related to the microscopic abnormalities that affect how oxygen is exchanged from the lungs to the red blood cells.
The results of the study were published in the journal Radiology and reveal a potential cause for long-COVID symptoms.
“By understanding the cause, team members responsible for patient care have been able to target treatment for these patients,” the press release reads.
Long COVID is characterized by the feeling of brain fog, breathlessness, fatigue and limited capacity to do normal day-to-day things. The symptoms can last weeks or months following initial infection.
“I think it is always a conundrum when someone has symptoms, but you can't identify the problem. Because if you can't identify the problem, you can't identify solutions,” said Parraga, Tier 1 Canada research chair in lung imaging to transform outcomes at Western’s Schulich School of Medicine & Dentistry.
By having study participants inhale polarized xenon gas while inside an MRI, researchers could see in real time the function of the 300-500 million tiny alveolar sacs, which are about 1/5 of a mm in diameter and are responsible for delivering oxygen to the blood.
“With our MRI technique, we can watch in real-time the air moving through the alveolar membrane and through to the blood cells; and we can actually see the function of the tiny alveolar sacs in the lungs,” said Parraga. “What we saw on the MRI was that the transition of the oxygen into the red blood cells was depressed in these symptomatic patients who had had COVID-19, compared to healthy volunteers.”
Study participants with suspected long COVID were recruited from two London, Ont., hospitals -- London Health Sciences Centre's (LHSC) urgent COVID-19 care clinic and St. Joseph’s Health Care's post-acute COVID-19 program.
According to the release, some study participants were still symptomatic after 35 weeks. A one-year follow-up is now underway to better understand the results.
The study was done in collaboration with LHSC, St. Joseph’s, Lakehead University, McMaster University, Toronto Metropolitan University and Sick Kids Hospital in Toronto.
CTVNews.ca Top Stories
Why drivers in Ontario, Quebec and Atlantic Canada will see a gas price spike, and other Canadians won't
Drivers in Eastern Canada face a big increase in gas prices because of various factors, especially the higher cost of the summer blend, industry analysts say.
'A living nightmare': Winnipeg woman sentenced following campaign of harassment against man after online date
A Winnipeg woman was sentenced to house arrest after a single date with a man she met online culminated in her harassing him for years, and spurred false allegations which resulted in the innocent man being arrested three times.
How to avoid the trap of becoming 'house poor'
The journey to home ownership can be exciting, but personal finance columnist Christopher Liew warns about the trappings of becoming 'house poor' -- where an overwhelming portion of your income is devoured by housing costs. Liew offers some practical strategies to maintain better financial health while owning a home.
It's the biggest election in history. Here's why few Indians in Canada will take part
In the Indian general election that gets underway on Friday, almost a billion people are eligible to vote, but a vast majority of the overseas Indian community in Canada won't be casting a ballot.
McDonald's customers left with 'zero value' collection of free hot drink stickers after company ends program
It took years for Vinnie Deluca to collect more than 400 cards worth of free McDonald's McCafe coffee, a collection that now has "zero value" after the company discontinued the program.
Jury selection in Trump hush money trial faces pivotal stretch as former U.S. president returns to court
Jury selection in the hush money trial of Donald Trump enters a pivotal and potentially final stretch Thursday as lawyers look to round out the panel of New Yorkers that will decide the first-ever criminal case against a former president.
Toxic forever chemicals in drinking water: Is Canada doing enough?
As the United States sets its first national limits on toxic forever chemicals in drinking water, researchers say Canada is lagging when it comes to regulations.
Where did the gold go? Crime expert weighs in on unfolding Pearson airport heist investigation
Almost 7,000 bars of pure gold were stolen from Pearson International Airport exactly one year ago during an elaborate heist, but so far only a tiny fraction of that stolen loot has been found.
Biden scores endorsements from Kennedy family, looking to shore up support against Trump and RFK Jr.
U.S. President Joe Biden will accept endorsements from at least 15 members of the Kennedy political family during a campaign stop in Philadelphia on Thursday as he aims to undermine Donald Trump and marginalize the candidacy of Robert F. Kennedy Jr.