One person is dead and three others were taken to hospital after a three-vehicle collision south of Exeter.

Police, South Huron fire and EMS responded to London Road (Highway 4) between Kirkton Road and Crediton Road for a crash that occurred just after 6 a.m. Wednesday.

According to investigators, a northbound Jeep Wrangler crossed the centre line and sideswiped a southbound Toyota Solara before crashing head-on with a southbound Chrysler Intrepid.

Police say the driver of the Intrepid, 46-year-old Mary-Jane Forrester of South Huron, was pronounced deceased at the scene.

The driver of the Wrangler, 19-year-old Maarten Deregt of Middlesex Centre, was transported to hospital with serious, but non-life-threatening injuries.

The driver and passenger in the Solara were taken to hospital for observation but later released.

Police continue to investigate the crash.

"We are looking for any information from the public. If there was anybody in the area that might have witnessed the collision, certainly we would encourage them to give us a call," says OPP Const. Jamie  Stanley.

The toll-free number is 1-888-310-1122.

London Road was closed for about nine hours between Kirkton Road and Crediton Road for the investigation.